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  • 2022_2021

      August 2022

      • 8-26-2022: Wu, X.*, Wang, X., Chen, W., Liu, X., Lin, Y., Wang, F., Liu, L., Meng, Y.* (2022). A microRNA-microRNA crosstalk network inferred from genome-wide single nucleotide polymorphism variants in natural populations of Arabidopsis thaliana. Frontiers in plant science, 13:958520. doi: 10.3389/fpls.2022.958520. [Link]

      June 2022

      • 恭喜张琪顺利通过博士论文答辩!恭喜陈柯娜和杨本光获得硕士学位!

      May 2022

      • 5-8-2022: Pei, S., Liu, Y., Li, W., Krichilsky, B., Dai, S., Wang, Y.,..., Pei, Z.M.*, Yuan, F.* (2022). OSCA1 is an osmotic specific sensor: a method to distinguish Ca(2+) -mediated osmotic and ionic perception. New Phytologist, 235(4): 1665-1678. doi: 10.1111/nph.18217 [Link]
      • 5-3-2022: Wu, X.*, Yuan, F., Wang, X., Zhu, S., and Pei, Z. M.* (2022). Evolution of osmosensing OSCA1 Ca(2+) channel family coincident with plant transition from water to land. The Plant Genome, e20198. doi: 10.1002/tpg2.20198. [Link]
  • 2020_2019

      June 2020

      • 恭喜刘璐璐和刘源涛顺利通过博士学位论文答辩!王焱、陶琪和代世文获得硕士学位!

      February 2020

      • 2-19-2020: Wu, F., Chi, Y., Jiang, Z., Xu, Y., Xie, L., Huang, F., Wan, D., Ni, J., Yuan, F., Wu, X., Zhang, Y., Wang, L., Ye, R., Byeon, B., Wang, W., Zhang, S., Sima, M., Chen, S., Zhu, M., Pei, J., Johnson, D.M., Zhu, S., Cao, X., Pei, C., Zai, Z., Liu, Y., Liu, T., Swift, G.B., Zhang, W., Yu, M., Hu, Z., Siedow, J.N., Chen, X., and Pei, Z.M.* (2020) Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis. Nature, 578(7796), 577-581. [Link]

      July 2019

      • 7-31-2019: Jiang, Z., Zhou, X., Tao, M., Yuan, F., Liu, L., Wu, F., Wu, X., Xiang, Y., Niu, Y., Liu, F., Li, C., Ye, R., Byeon, B., Xue, Y., Zhao, H., Wang, H.N., Crawford, B.M., Johnson, D.M., Hu, C., Pei, C., Zhou, W., Swift, G.B., Zhang, H., Vo-Dinh, T., Hu, Z., Siedow, J.N., and Pei, Z.M.* (2019) Plant cell-surface GIPC sphingolipids sense salt to trigger Ca(2+) influx. Nature, 572(7769): 341-346. [Link]

      June 2019

      • 恭喜张庶、裴宋雨和池源顺利通过博士学位论文答辩!王梦云、王茜、李?珂和王柏荣获得硕士学位!

      April 2019

      • 4-3-2019: Teng Y.*, Liang Y., Wang M. Mai H. and Ke L. (2019) Nitrate Transporter 1.1 is involved in regulating flowering time via transcriptional regulation of FLOWERING LOCUS C in Arabidopsis thaliana. Plant Science, 284:30-36. [PubMed]
  • 2018_2017

      September 2018

      • 9-05-2018: Paper published in Gene. Wang M. and Teng Y.* (2018) Genome-wide identification and analysis of MICU genes in land plants and their potential role in calcium stress. Gene, 670:174-181. [Link]

      June 2018

      • 恭喜朱易华顺利获得浙大-杭师大联合培养博士学位!蔡云飞、申洋、梁宜、王超、万?和杨艺获得硕士学位!

      July 2017

      • 7-26-2017: Paper published in Frontiers in Physiology. Wu, X.*, Wu, F.H., Wu, Q., Zhang, S., Chen, S. and Sima, M. (2017) Phylogenetic and Molecular Evolutionary Analysis of Mitophagy Receptors under Hypoxic Conditions. Frontiers in physiology , 8:539. [Full Text]

      February 2017

      • 2-25-2017: Paper accepted in Plant and Soil. Yibo Teng* (2017) Haoqiang Cui, Mengyun Wang and Xunyan Liu, Nitrate Reductase is regulated by CIRCADIAN CLOCK-ASSOCIATED1 in Arabidopsis thaliana. Plant and Soil, doi:10.1007/s11104-017-3208-y.

      January 2017

      • 1-31-2017: Xiaoqiang Cao, Zhonghao Jiang, Yanyan Yi, Yi Yang, Liping Ke, Zhen-Ming Pei, Shan Zhu* (2017) Biotic and Abiotic Stresses Activate Different Ca 2+ Permeable Channels in Arabidopsis, Frontiers in Plant, 8:83. [Full Text]
  • 2016-2015

      May 2016

      • 05-11-2016: 第二届植物环境感受国际研讨会 (2016)  "The Second Symposium on Plant Environmental Sensing"

        报告人: Dr. Kazuyuki Kuchitsu, Dr. June M.Kwak, Dr. Junxian He(何军贤), Dr. Tieliu Shi(石铁流) and Dr. Houfeng Zheng(郑厚峰)

        主持人: Dr. Zhenming Pei(裴真明)

        时间:2016年5月11日(周三), 12:50-17:00

        地点:杭州师范大学下沙校区叙伦厅

        研讨会具体安排:

        12:50-13:00 Opening remarks from Prof. Zhenming Pei

        13:00-13:45 Prof. Kazuyuki Kuchitsu, title "Regulation of plant development and stress responses by the ROS-Ca2+ signaling network and autophagy"

        13:45-14:30 Prof. Junxian He (何军贤), title "Brassinosteroid signalling : what is next?"

        14:30-14:45 Coffer/tea break

        14:45-15:30 Prof. June M.Kwak, title "Global Climate Change, Cell Signaling, and Sustainability"

        15:30-16:15 Prof. Tieliu Shi (石铁流), title "Comprehensive idendentification and function study of Arabidopsis chloroplast proteome through systems biology approach"

        16:15-17:00 Prof. Houfeng Zheng (郑厚峰), title "Big Data Analytics in Genetic Medicine: Toward Precision Medicine" " Comprehensive idendentification and function study of Arabidopsis chloroplast proteome through systems biology approach"

         

        报告人简介:
        • Prof. June M.Kwak
          韩国科技研究所 (DaeguGyeongbuk,DGIST) 及韩国基础研究所 (IBS) 教授、美国马里兰大学兼职教授。主要从事植物钙信号传导的研究,在 Ca2+信号转导途径在保卫细胞中的通路及引起 ROS 分子机制的研究中取得重要成果。近年来,在 Nature, Plant Cell, PNAS, EMBO J, Plos Biology 等国际权威杂志发表文章数十篇,在相关领域具有很高影响力。
          Position: Associate Professor & Group Leader
          Affiliation: Department of New Biology/DGIST, Center for Plant Senescence and Life History/IBS, Techno Jungang-daero 333, Hyeongpung-myun, Daegu 711-873, Republic of Korea.
          URL: URL: http://www.kwaklab.org/umd

          Selected Publications:

          (1) C Zhang, Q Xie, R Anderson, G Ng, N Seitz, CR McClung, JM McDowell, D Kong, JM Kwak and H Lu (2013) Crosstalk between the circadian clock and innate immunity in Arabidopsis. PLoS Pathogen doi: http://dx.doi.org/10.1371/journal.ppat.1003370

          (2) F. Villiers and JM Kwak (2013) Rapid apoplastic pH measurement of Arabidopsis leaves using a fluorescent dye. Plant Sig. & Behav. 8: e22587141-143.

          (3) D Cho, *F Villiers, L Kroniewicz, S Lee, Y Seo, K Hirschi, N Leonhardt and JM Kwak (2012) Vacuolar CAX1 and CAX3 influence auxin transport in guard cells via regulation of apoplastic pH. Plant Physiol. 160: 1293-1302.

          (4) F Jammes, CJ Song, D Shin, S Munemasa, K Takeda, D Gu, D Cho, S Lee, R Giordo, S Sritubtim, N Leonhardt, EB Ellis, Y Murata and JM Kwak (2009) Two MAP kinases, MPK9 and MPK12, are preferentially expressed in guard cells and positively regulate ROS-mediated ABA signaling. Proc. Nat’l. Acad. Sci. USA, 106: 20520-20525.

          (5) JM Kwak, J Moon, Y Murata, K Kuchitsu, N Leonhardt, A DeLong and JI Schroeder (2002) Disruption of a guard cell-expressed protein phosphatase 2A regulatory subunit, RCN1, confers abscisic acid insensitivity in Arabidopsis. Plant Cell, 14, 2849-2861.

        • Prof. Kazuyuki Kuchitsu
          日本东京理科大学应用生物科学系教授,主要从事钙信号及活性氧在调控植物逆境胁迫中的生理功能研究,曾获日本生物成像协会和日本植物生理学家学会的青年科学家奖,并担任多个国际学术期刊编委。
          Affiliation: Department of Applied Biological Science, Tokyo University of Science, Japan.
          Professional activities and services: 2005-present: Editor, Bioimages; 2007-2011: Editor, Journal of Plant Research

          Selected Publications:
          (1) Kurusu et al. (2014) OsATG7 is required for autophagy-dependent lipid metabolism in rice postmeiotic anther development. Autophagy 10(5):878-88. doi: 10.4161/auto.28279.

          (2) Karkonen A, Kuchitsu K (2014) Reactive oxygen species in cell wall metabolism and development in plants. Phytochemistry 112(2015): 22-32.

          (3) Hanamata S, Kurusu T, Kuchitsu K (2014) Roles of autophagy in male reproductive development in plants. Frontiers in Plant Science, section Plant Cell Biology 5(457) doi: 10.3389/fpls.2014.00457.

          (4) Hamada H, Kurusu T, Nokajima H, Kiyoduka M, Yano K, Kuchitsu K (2014) Regulation of xylanase elicitor-induced expression of defense-related genes involved in phytoalexin biosynthesis by a cation channel OsTPC1 in suspension-cultured rice cells. Plant Biotech 31(4):329-334.

          (5) Kaya H, Nakajima R, Iwano M, Kanaoka MM, Kimura S, Takeda S, Kawarazaki T, Senzaki E, Hamamura Y, Higashiyama T, Takayama S, Abe M, Kuchitsu K (2014) Ca2+-activated ROS production by Arabidopsis RbohH and RbohJ is essential for proper pollen tube tip growth. Plant Cell 26(3): 1069-1080.

          (6) Dadacz-Narloch B, Kimura S, Kurusu T, Farmer EE, Becker D, Kuchitsu K, Hedrich R (2013) On the cellular site of two-pore channel TPC1 action 1 in the Poaceae. New Phytol. 200(3): 663-674.

          (7) Kurusu T, Kuchitsu K, Nakano M, Nakayama Y, Iida H (2013) Plant mechanosensing and Ca2+ transport. Trends in Plant Science 18: 227-233.

          (8) Hamada H#, Kurusu T#, Okuma E, Nokajima H, Kiyoduka M, Koyano T, Sugiyama Y, Okada K, Koga J, Saji H, Miyao A, Hirochika H, Yamane H, Murata Y, Kuchitsu K (2012) Regulation of a proteinaceous elicitor-induced Ca2+ influx and production of phytoalexins by a putative voltage-gated cation channel, OsTPC1, in cultured rice cells. J Biol. Chem. 287(13): 9931-9939.

        • 何军贤博士

          香港中文大学助理教授,主要从事植物讯息传递及抗逆机理研究。
          Position: Assistant Professor, School of Life Sciences, The Chinese University of Hong Kong.


          Selected Publications:
          (1) Li Q.F., C Wang, L Jiang, S Li, S.S.M Sun*. and J.X. He*. (2012) An interaction between BZR1 and DELLAs mediates direct signaling crosstalk between brassinosteroids and gibberellins in Arabidopsis. Sci Signal 5:ra72 (Summary/Abstract/Reprint/FullText) (Highlight by Nature Reviews)

          (2) Jiang L, Y. Wang, Q.F. Li, L.O. Bj?rn, J.X. He* and S.S. Li*. (2012) Arabidopsis STO/BBX24 negatively regulates UV-B signaling by interacting with COP1 and repressing HY5 transcriptional activity. Cell Res 22:1046-1057. (Evaluated by Faculty 1000)

          (3) Jiang L., Y. Wang, L.O. Bj?rn*, J.X. He* and S.S. Li*. (2012) Sensing of ultraviolet-B radiation by plants. Plant Signal & Behav 7:999-1003.

          (4) He, J.X., Gendron, J.M., Sun, Y., Gampala, S.L., Gendron, N., Sun, C.Q., and Wang, Z.Y. (2005) BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses. Science 307:1634-1638.

          (5) Wang, Z.Y. and He, J.X. (2004) Brassinosteroid signal transduction - choices of signals and receptors. Trends in Plant Sci 9: 91-96.

          (6) He, J.X., Fujioka, S., Li, T.C., Kang, S.G., Seto, H., Takatsuto, S.,Yoshida, S., and Jang, J.C. (2003) Sterols regulate development and gene expression in Arabidopsis. Plant Physiol 131:1258-1269.

          (7) He, J.X., JM Gendron, Y. Yang, J. Li, Z.Y. Wang. (2002) The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis. Proc. Natl. Acad. Sci. USA 99:10185-90.

        • 石铁流博士
          华东师范大学生命医学研究所和生命科学学院教授、博士生导师。从事生物信息学领域的研究工作,其研究工作受到了国际上相关领域专家的关注。

          Selected Publications:
          (1) Chen G, Wang C, Shi LM, Tong WD, Qu XF, Chen JW, Yang JM, Shi CP, Chen L, Zhou PY, Lu BX, Shi TL* Comprehensively identifying and characterizing the missing gene sequences in human reference genome with integrated analytic approaches. Human Genetics 132(8):899-911.

          (2) Chen G, Wang C, Shi LM, Qu XF, Chen JW, Yang JM, Shi CP, Chen L, Zhou PY, Ning BT, Tong WD, Shi TL* Incorporating the human gene annotations in different databases significantly improved transcriptomic and genetic analyses. RNA 19 : 479 - 489, 2012.

          (3) Liu YL, Li ZZ, Zhang MX, Deng YP, Yi ZH, Shi TL* Exploring the Pathogenetic Association between Schizophrenia and Type 2 Diabetes Mellitus Diseases based on Pathway Analysis. BMC Medical Genomics, 6(Suppl 1):S17, 2013.

          (4) Ruichao Xue, Zhao Fang, Meixia Zhang, Zhenghui Yi, Tieliu Shi* TCMID: Traditional Chinese Medicine Integrative Database for Herb Molecular Mechanism Analysis. Nucleic Acids Research 41(D1): D1089-D1095, 2013.

          (5) Li P, Zang W, Li Y, Xu F, Wang J and Shi TL*. AtPID: the overall hierarchical functional protein interaction network interface and analytic platform for Arabidopsis. Nucleic Acids Res. 39(Database Issue): D1130-1133, 2011.

          (6) Wang L-S, Xiong Y-Y, Sun Y-H, Fang Z-Y, Li L, Ji H-B, Shi TL*. HLungDB: an integrated database of human lung cancer research. Nucleic Acids Res. 38: D665-669, 2010.

        • 郑厚峰博士
          国家“千人计划”青年专家。杭州师范大学教授、杭州师范大学附属医院医师,致力于复杂疾病易感基因的遗传学研究。在 Nature 、 Nature Genetics 和 American Journal of Human Genetics 等遗传学领域顶级期刊发表论文 40 多篇。

          Selected Publications:
          (1) Carss KJ, Stevens E, Foley AR, Cirak S, Riemersma M, Torelli S, Hoischen A, Willer T, van Scherpenzeel M, Moore SA et al. 2013. Mutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of alpha-dystroglycan. Am J Hum Genet 93(1): 29-41..

          (2) Schmidts M, Hou Y, Cortes CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza JM, van Beersum SE et al. 2015. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport. Nature communications 6: 7074.

          (3) Timpson NJ, Walter K, Min JL, Tachmazidou I, Malerba G, Shin SY, Chen L, Futema M, Southam L, Iotchkova V et al. 2014. A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans. Nature communications 5: 4871.

          (4) Zheng H, Zhao Y. 2015. Association of CYP1A1 MspI polymorphism in the esophageal cancer risk: a meta-analysis in the Chinese population. European journal of medical research 20: 46.

          (5) Zheng HF, Forgetta V Hsu YH Estrada K Rosello-Diez A Leo PJ Dahia CL Park-Min KH Tobias JH Kooperberg C et al. 2015. Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature 526(7571): 112-117.

          (6) Zheng HF, Tobias JH, Duncan E, Evans DM, Eriksson J, Paternoster L, Yerges-Armstrong LM, Lehtimaki T, Bergstrom U, Kahonen M et al. 2012b. WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet 8(7): e1002745.

      January 2016

      • 01-30-2016: Pang, E.*, Wu, X., and Lin, K. (2016) Different evolutionary patterns of SNPs between domains and unassigned regions in human protein-coding sequences. Molecular genetics and genomics, DOI:10.1007/s00438-016-1170-7. [Full Text]

      September 2015

      • 9-7-2015: 欢迎裴宋雨、朱易华两位博士研究生,以及万?、梁宜、王超、申洋、杨艺和蔡云飞六位硕士研究生加入CPESen! 同时祝贺俞瀚炳、周晓萍和张岩岩三位同学取得硕士学位,顺利毕业!

      August 2015

      • 8-30-2015: Liu X., Cui H., Li A., Zhang M., and Teng Y.* (2015) The nitrate transporter NRT1.1 is involved in iron deficiency responses in Arabidopsis. Journal of Plant Nutrition and Soil Science, 178(4): 601-608. [Full Text]

      May 2015

      • 05-24-2015: 第一届植物环境感受国际研讨会 (2015)  "The First Symposium on Plant Environmental Sensing"

        报告人:Dr. Rainer Hedrich, Dr. Jian-Kang Zhu, Dr. Kazuyuki Kuchitsu and Dr. Zhen-Ming Pei

        时间:2015年5月24日(周日), 10:00-17:00

        地点:杭州师范大学下沙校区图书馆10层会议厅

        主办方:杭州师范大学 生命与环境科学学院

        承办方:植物环境感受研究中心 (CPESen, Center for Plant Environmental Sensing)

        研讨会具体安排:

        10:00-11:00 Rainer Hedrich, title "Ion Channels in Plants"

        11:00-11:15 Coffer/tea break

        11:15-12:00 Zhen-Ming Pei, title "Plant Water Sensors"

        12:00-14:00 lunch in the university guest restaurant

        14:00-15:00 Jiang-Kang Zhu, title "Abiotic Stress Signaling"

        15:00-15:15 Coffer/tea break

        15:15-16:15 Kazuyuki Kuchitsu, title "Regulation of Plant Immunity, Development and Reproduction by ROS-Ca2+ Signaling Network and Autophagy"

        16:20-16:50 Tour to the Center for Plant Environmental Sensing

        报告人简介:

        • Prof. Dr. Rainer Hedrich
          德国维尔茨堡大学植物学系系主任、教授,植物离子通道研究领域开创者,在植物信号传导和离子通道研究方面具有很高的造诣,是世界动植物科学领域发表论文引用率最高的科学家之一。
          Position: Professor and Head of Department
          Affiliation: Julius-von-Sachs-Institute for Biosciences, University of Würzburg, Germany.
          Awards: 2003, highly cited researcher among 250 in animal and plant sciences, ISI Web of Knowledge (http://isi1.isiknowledge.com/portal.cgi); 2010, ERC Advanced Grand Award

          Five Most Important Publications:

          (1) Maierhofer T, Diekmann M, Offenborn JN, Lind C, Bauer H, Hashimoto K, Al-Rasheid KAS, Luan S, Kudla J, Geiger D, Hedrich R (2014) Site- and kinase-specific phosphorylation-mediated activation of SLAC1, a guard cell anion channel stimulated by abscisic acid. Sci Signal 7: ra86

          (2) Scherzer S, Krol E, Kreuzer I, Kruse J, Karl F, von Ruden M, Escalante-Perez M, Muller T, Rennenberg H, Al-Rasheid KA, Neher E, Hedrich R (2013) The Dionaea muscipula ammonium channel DmAMT1 provides NH 4 + uptake associated with Venus flytrap's prey digestion. Curr Biol 23: 1649-1657

          (3) Bauer H, Ache P, Lautner S, Fromm J, Hartung W, Al-Rasheid KA, Sonnewald S, Sonnewald U, Kneitz S, Lachmann N, Mendel RR, Bittner F, Hetherington AM, Hedrich R (2012) The stomatal response to reduced relative humidity requires guard cell-autonomous ABA synthesis. Curr Biol 23: 53-57

          (4) Escalante-Perez M, Krol E, Stange A, Geiger D, Al-Rasheid KA, Hause B, Neher E, Hedrich R (2011) A special pair of phytohormones controls excitability, slow closure, and external stomach formation in the Venus flytrap. Proc Natl Acad Sci USA 108: 15492-15497

          (5) Geiger D, Maierhofer T, Al-Rasheid KA, Scherzer S, Mumm P, Liese A, Ache P, Wellmann C, Marten I, Grill E, Romeis T, Hedrich R (2011) Stomatal closure by fast abscisic acid signaling is mediated by the guard cell anion channel SLAH3 and the receptor RCAR1. Science Signal 4: ra32

        • Prof. Jian-Kang Zhu
          美国科学院院士,普渡大学教授,上海植物逆境生物学研究中心主任,是植物抗逆分子生物学领军人物,在植物抗干旱、盐碱与低温方面做出了杰出成就,是世界植物科学领域发表论文引用率最高的科学家之一。
          Position: Distinguished Professor of Plant Biology
          Affiliation: Departments of Horticulture and Landscape Architecture and Biochemistry, Purdue University.

          Selected Publications:
          (1) Yamamuro C, Miki D, Zheng Z, Ma J, Wang J, Yang Z, Dong J, Zhu JK. 2014. Overproduction of stomatal lineage cells in Arabidopsis mutants defective in active DNA demethylation. Nat Commun. 5:4062.

          (2) Zhao Y, Xing L, Wang X, Hou YJ, Gao J, Wang P, Duan CG, Zhu X, Zhu JK. 2014. The ABA receptor PYL8 promotes lateral root growth by enhancing MYB77-dependent transcription of auxin-responsive genes. Sci Signal. 7:ra53.

          (3) Wang D, Qu Z, Adelson DL, Zhu JK, Timmis JN. 2014. Transcription of nuclear organellar DNA in a model plant system. Genome Biol Evol. 6:1327-1334.

          (4) Feng Z, Mao Y, Xu N, Zhang B, Wei P, Yang DL, Wang Z, Zhang Z, Zheng R, Yang L, Zeng L, Liu X, Zhu JK. 2014. Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis. Proc Natl Acad Sci U S A. 111:4632-4637.

          (5) Lei M, La H, Lu K, Wang P, Miki D, Ren Z, Duan CG, Wang X, Tang K, Zeng L, Yang L, Zhang H, Nie W, Liu P, Zhou J, Liu R, Zhong Y, Liu D, Zhu JK. 2014. Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns. Proc Natl Acad Sci U S A. 111:527-532.

          (6) Zhang H, He X, Zhu JK. 2013 .RNA-directed DNA methylation in plants: Where to start? RNA Biol. 10:1593-1596.

          (7) Yin P, Li Q, Yan C, Liu Y, Liu J, Yu F, Wang Z, Long J, He J, Wang HW, Wang J, Zhu JK, Shi Y, Yan N.. 2013. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature. 504:168-171.

        • Prof. Kazuyuki Kuchitsu
          日本东京理科大学应用生物科学系教授,主要从事钙信号及活性氧在调控植物逆境胁迫中的生理功能研究,曾获日本生物成像协会和日本植物生理学家学会的青年科学家奖,并担任多个国际学术期刊编委。
          Affiliation: Department of Applied Biological Science, Tokyo University of Science, Japan.
          Professional activities and services: 2005-present: Editor, Bioimages; 2007-2011: Editor, Journal of Plant Research

          Selected Publications:
          (1) Kurusu et al. (2014) OsATG7 is required for autophagy-dependent lipid metabolism in rice postmeiotic anther development. Autophagy 10(5):878-88. doi: 10.4161/auto.28279.

          (2) Karkonen A, Kuchitsu K (2014) Reactive oxygen species in cell wall metabolism and development in plants. Phytochemistry 112(2015): 22-32.

          (3) Hanamata S, Kurusu T, Kuchitsu K (2014) Roles of autophagy in male reproductive development in plants. Frontiers in Plant Science, section Plant Cell Biology 5(457) doi: 10.3389/fpls.2014.00457.

          (4) Hamada H, Kurusu T, Nokajima H, Kiyoduka M, Yano K, Kuchitsu K (2014) Regulation of xylanase elicitor-induced expression of defense-related genes involved in phytoalexin biosynthesis by a cation channel OsTPC1 in suspension-cultured rice cells. Plant Biotech 31(4):329-334.

          (5) Kaya H, Nakajima R, Iwano M, Kanaoka MM, Kimura S, Takeda S, Kawarazaki T, Senzaki E, Hamamura Y, Higashiyama T, Takayama S, Abe M, Kuchitsu K (2014) Ca2+-activated ROS production by Arabidopsis RbohH and RbohJ is essential for proper pollen tube tip growth. Plant Cell 26(3): 1069-1080.

          (6) Dadacz-Narloch B, Kimura S, Kurusu T, Farmer EE, Becker D, Kuchitsu K, Hedrich R (2013) On the cellular site of two-pore channel TPC1 action 1 in the Poaceae. New Phytol. 200(3): 663-674.

          (7) Kurusu T, Kuchitsu K, Nakano M, Nakayama Y, Iida H (2013) Plant mechanosensing and Ca2+ transport. Trends in Plant Science 18: 227-233.

          (8) Hamada H#, Kurusu T#, Okuma E, Nokajima H, Kiyoduka M, Koyano T, Sugiyama Y, Okada K, Koga J, Saji H, Miyao A, Hirochika H, Yamane H, Murata Y, Kuchitsu K (2012) Regulation of a proteinaceous elicitor-induced Ca2+ influx and production of phytoalexins by a putative voltage-gated cation channel, OsTPC1, in cultured rice cells. J Biol. Chem. 287(13): 9931-9939.

        • Prof. Zhen-Ming Pei
          国家“千人计划”入选者,杭州师范大学特聘教授,主要从事植物逆境感受、钙信号转导分子机理方面的研究。在植物科学领域取得了多方面的突破性进展和重要学术成就。
          See Pei Webpage for Detail.

        会议剪影:

      March 2015

      • 03-27-2015: 学术报告 “中国水稻种业—分子育种 大平台的建设
        报告人:应继锋博士, 华智水稻高级科学家
        时间:2015年4月3日(周五), 上午10:30
        地点:行政楼804
        邀请人:裴真明教授

        专家简介:应继锋博士,1985年获得南京农业 大学农学学士,1990年硕士研究生毕业于泰国清迈大学农学专业,1997年博士研究生毕业于菲律宾大学(国际水稻所)农学专业。博士后在加拿大圭 尔夫大学从事作物生理学研究。先后在中国水稻研究所担任助理研究员、加拿大Performance Plants Inc. 担任研究科学家、美国陶氏化学公司担任研究科学家、美国巴斯夫植物科学公司担任高 级科学家等种业企业工作。具有5年跨国种业大公司研发管理经验,专长于作物生理学、农学性状评估、数据资料分析等方面。具有丰富的重要农学性状基因 (抗旱,氮肥利用,高产,重叠优良转基因)的 鉴定和分类等研究经验。现任华智水稻高级科学家。
  • 2014-2013

      October 2014

      • 10-13-2014: 学术报告 “Balance Between Growth and Defense: Timing of Plant Immune System
        报告人:王伟博士, 美国爱荷华州立大学植物病理和微生物学系
        时间:2014年10月13日(周一),下午15:30-17:30
        地点:生科院5号实验楼 4楼东会议室
        主持人:裴真明教授

        专家简介:王伟博士2007年毕业于复旦大学生物技术专业,获得学士学位,2012年于美国杜克大学生物系董欣年教授实验室获得博士学位,并且于同一实验室完成其博士后研究工作。近期成为美国爱荷华州立大学植物病理和微生物学系教授。王伟博士开创性的探索了生物钟调控植物系统免疫这一研究领域,这一研究成果发表在《Nature》杂志上,并且被包括纽约时报,BBC野生动物杂志在内的多家知名媒体报道。王伟博士通过生物化学和统计学模型分析,找到植物激素水杨酸受体NPR3,NPR4。最近,王伟博士还发现水杨酸可以强化生物钟,这种强化可以调整植物获得性免疫的时机。揭示了水杨酸出发的无规律氧化还原反应可以被生物钟整合并且转化成震荡型的输出来调控免疫应答的理论。

        代表性论著:
        1. Zhou, M.*, Wang, W.*, Karapetyan, S., Mwimba, M., Marqués, J.,Buchler, N., Dong, X. Redox regulates the circadian clock to balance immunity and fitness, (*co-first author, In revision in Nature)
        2. Wang, S.*, Anderson, L.*, Zebell, S.*, Gu, Y., Wang, W., Wang, J., Dong, X. The CKI-RB-E2F cell cycle signaling pathway mediates plant effector-triggered immunity, Cell Host & Microbe (*co-first author, In press)
        3. Yan, S., Wang, W.,Marqués, J.,Mohan, R., Saleh, A., Durrant, W., Song, J., Dong, X. Salicylic acid activates DNA damage responses to potentiate immunity in plants, Molecular Cell (2013) 52, 602-610
        4. Fu, Z.*, Yan, S.*, Saleh, A.*, Wang, W., Ruble, J., Oka, N., Mohan, R., Spoel, S., Tada, Y., Zheng, N., Dong, X. NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants, Nature (2012) 486, 228-232 (*co-first author)
        5. Wang, W.*, Barnaby, J.*, Tada, Y., Li, H., T?r, M., Caldelari, D., Lee, D., Fu, X., Dong, X. Timing of plant immune responses by a central circadian regulator, Nature(2011) 470, 110-114 (*co-first author)

      August 2014

      • 8-30-2014: 欢迎张庶(博士生)、买华晨、徐媛媛和霍晓迎四位新同学加入CPESen! 同时祝贺崔浩强、李安娜和沈燕霞三位同学毕业!

      • 8-27-2014: Publication on Nature !
        Yuan, F., Yang, H., Xue, Y., Kong, D., Ye, R., Li, C., Zhang, J., Theprungsirikul, L., Shrift, T., Krichilsky, B., Johnson, D.M., Swift, G.B., He, Y., Siedow, J.N. and Pei, Z.M.* (2014) OSCA1 mediates osmotic-stress-evoked Ca increases vital for osmosensing in Arabidopsis. Nature. doi:10.1038/nature13593. [Full Text]

        本中心在植物感受干旱机制的研究上取得较大突破!本中心成员远方等与美国杜克大学通过多年努力,合作建立了一套全新的突变体筛选体系,成功地用模式植物拟南芥筛选到干旱感受相关的遗传突变体,并且克隆了感受干旱的感受器基因。相关研究成果于2014年8月27日在《自然》杂志上发表。

        在过去20年中,人们对植物通过细胞内钙浓度增加来响应各种非生物和生物刺激的理解有了许多进步,但相应的感受干旱的钙离子通道的蛋白仍然不知道。该研究利用正向遗传筛选干旱激活细胞内钙离子浓度增加的方法获得缺陷型突变体,并克隆到相关基因,命名为干旱感受器OSCA1。OSCA1属于一个功能未知的基因家族。该研究进一步证明OSCA1形成一个非选择性阳离子通道,在质膜上可通透钙离子,并被干旱激活。OSCA1参与干旱信号诱导的早期信号事件(钙增加,5秒),干旱介导生理过程(气孔关闭,30分钟),以及持续干旱对生长和发育的影响(根生长,11天)。因此OSCA1被认为是植物干旱感受机制中的一个最重要成分。

        随着全球气候变化,高温及其伴随的干旱将严重影响世界农作物生产及森林植被的生态和分布。该研究从植物感知干旱的受体出发,可真正探讨植物感应水条件变化的分子机制。通过改变和调节基因的方式改变农作物、牧草、森林树种等植物对干旱感受机制,培育出抵抗这些逆境的植物。同时,对植物感受器OSCA1的研究可揭示全球环境变化背景下植物适应性的产生与动态变化机理。总体而言,这些研究将有利于提高我国的粮食安全和植物生态系统安全,并且有助于稳步提高我国人居健康环境。

        这项研究是在裴真明博士的领导下,由国内外多个课题组共同努力,历时多年完成。该研究工作获得国家自然科学基金、浙江省自然科学基金及校攀登工程的支持与资助。

      • 8-20-2014: 祝贺刘训言获得2014年度国家自然科学基金青年基金!

      July 2014

      • 07-06-2014: 学术报告 “Recombination suppression keeps hybridizing species separate
        报告人:Mohamed Noor 教授, 美国杜克大学 (Duke University)
        时间:2014年7月6日(周日),下午15:00-16:30
        地点:生科院5号实验楼 4楼东会议室
        主持人:裴真明教授

        专家简介:Mohamed Noor教授1971年1月1日出生于澳大利亚。Mohamed Noor教授于1996年获得芝加哥大学生态与进化系的博士学位。现为杜克大学生物系系主任,长期从事进化遗传学的研究。Mohamed Noor将果蝇物种作为模式生物,利用分子遗传手段和大量的全基因组序列,关心物种分化的科学问题,专注于引起不同物种之间发生基因交换的进化驱动力的研究。除此之外,MohamedNoor教授还兼任多个国际重要期刊的编委,并在高水平SCI期刊上发表论文150余篇,包括Nature, Science, PNAS, PLOS Biology, Molecular Biology and Evolution等期刊,在国际学术上具有很高的威望,获得了进化领域具有权威的“达尔文-华莱士”奖章。

      June 2014

      • 6-30-2014: Publication on line
        Wu, X.*, Wu, F.H., Wang, X., Wang, L., Siedow, J.N., Zhang, W. and Pei, Z.M.* (2014) Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING. Nucleic Acids Research. doi: 10.1093/nar/gku569. [Full Text]
      • 06-27-2014: 学术报告 “The establishment of zygotic transcription and chromatin organization during Drosophila early embryogenesis
        报告人:陈凯博士, 美国Stowers Institute
        时间:2014年6月27日(周五),下午15:00-17:00
        地点:生科院5号实验楼 四楼东会议室

        专家简介:陈凯博士,1983年1月出生于江西九江。2001年9月至2005年7月在兰州大学国家生物学基础学科人才培养与科学研究基地完成本科学习。2005年9月在中国科学院昆明动物研究所师从季维智教授开始了硕士研究生学习,从事动物发育研究。2008年1月前往美国Stowers Institute学习并于2013年1月取得博士学位,目前继续在该实验室从事博士后研究。2014年7月将在美国加州伯克利分校的Levine实验室利用海鞘为模式生物,进一步开展合子基因组启动在脊索动物中如何被调控的及进化的的研究。 陈凯博士十余年研究工作已取得显著成果。博士期间利用功能基因组的手段,研究了合子基因组启动的转录调控和染色质行程,发现了100多个早期合子基因,其中包括40多个未知功能的新基因,部分工作已发表在生命科学领域新的顶尖开源期刊eLIFE上。目前国际上多家实验室正利用此数据和技术进行类似研究, 包括近几个月的Nature和Developmental Cell在斑马鱼中也有类似的发现。知名综述期刊Trend in Genetics也邀请陈凯博士和他的导师撰写相关综述。

        代表性论著:
        1. Wang,YL., Duttke, S., Chen, K., Johnston, J., Kassavetis, G., Zeitlinger, J., Kadonaga, J. TRF2, and not TBP, Mediates the Transcription of Ribosomal Protein Genes. Gene & Development Accepted and will be available at www.genesdev.org on 6/23
        2. Chen, K., Johnston, J., Shao, W., Meier, S., Staber, C., Zeitlinger, J. (2013)A global change in RNA polymerase II pausing during Drosophila genome activation. eLIFE 2:e00861.
        3. Lagha, M., Bothma, J.P., Esposito, E., Stefanik, L., Tsui, C., Johnston, J., Chen, K., Gilmour, D.S., Zeitlinger, J., and Levine, M. (2013). Paused Pol II Coordinates Tissue Morphogenesis in the Drosophila Embryo. Cell 153, 976-987.
        4. Gaertner, B., Johnston, J., Chen, K., Wallaschek, N., Paulson, A., Garruss, A.S., Gaudenz, K., De Kumar, B., Krumlauf, R., and Zeitlinger, J. (2012). Poised RNA polymerase II changes over developmental time and prepares genes for future expression. Cell Rep. 2, 1670-1683.
        5. Wang, S., Shen, Y., Yuan, X., Chen, K., Guo, X., Chen, Y., Niu, Y., Li, J., Xu, R.-H., Yan, X., et al. (2008). Dissecting signaling pathways that govern self-renewal of rabbit embryonic stem cells. J. Biol. Chem. 283, 35929-35940.

        大会及应邀报告:
        2014年5月28日 昆明科灵生物科技有限公司 中国昆明
        2014年5月6-9日 冷泉港亚洲会议:表观遗传,染色质和转录 中国苏州
        2013年3月14-15日 Stowers Institute 年轻科学家展示日 堪萨斯城

      May 2014

      • 5-10-2014: Publication on line
        Ni, J., Shen, Y.X., Zhang, Y.Y. and Liu, Y.* (2014) Histological characterization of the lateral root primordium development in rice. Botanical Studies 55(1): 42. [Full Text]

      March 2014

      • 03-11-2014: 学术报告 “Molecular Mechanisms of Orai1 activation by STIM2”
        报告人:王友军教授,北京师范大学生命科学学院
        时间:2014年3月11日(周二),下午15:00-17:00
        地点:生科院5号实验楼 4楼东会议室

        专家简介:1997年毕业于烟台大学生化系,获学士学位;2000年于北京大学生命科学学院获得神经生理学专业硕士学位;2007年于美国马里兰大学帕克分校获得神经与认知专业专业博士学位,期间主要从事鲎腹光感受细胞内钙信号转导的分子机制的研究。博士毕业后,在美国费城天普大学生化系Gill实验室工作了六年(三年博士后,三年助理科学家)。期间从事钙离子通道及钙信号转导的分子机制的研究,2012年被聘为北京师范大学教授,并于2013年5月正式入职北京师范大学生命科学学院抗性基因资源与分子发育北京市重点实验室,并入选教育部2013年度“新世纪人才支持计划”及第五批“青年千人计划”。

        主要研究内容:钙离子通道,钙感受器及钙调控蛋白及其介导的钙信号在肿瘤及心血管疾病中作用的分子机制。利用荧光及钙成像、全细胞膜片钳技术及分子生物学方法,在动物细胞系,急性分离的小鼠细胞及基因敲除小鼠内研究TRP离子通道,L-型钙离子通道,Orai钙离子通道及STIM蛋白的相互作用及其介导钙信号的分子机制。重点研究他们及其介导的钙信号在肿瘤细胞增殖及血管损伤修复过程中的作用的分子机理。

        代表性论著:
        Wang, Y., Deng, X., Mancarella, S., Hendron, E., Eguchi, S., Soboloff J., Tang,X. and Gill, DL. (2010) The calcium store-sensor, STIM1, reciprocally controlsOraiand CaV1.2 channels. Science. 330(6000):105-9.

        Wang, Y.*, Deng, X.*, Zhou, Y.*,Hendron, E., Ritchie, M.F., Tang, X.D., Mancarella, S., Kurosaki, T., Mori, Y.,Soboloff, J., and Gill D.L. (2009) STIMProtein Coupling in the Activation of Orai Channels. Proc Natl. Acad. Sci. USA106(18):7391-6.

        Wang X*,Wang Y*#, Zhou Y, Hendron E, Mancarella S, Andrake MD,Rothberg BS, Soboloff J & Gill DL#. Distinct Orai-couplingdomains in STIM1 and STIM2 define the Orai-activating site. Nature Communications. 2014 (Accepted)

        Mancarella S,Wang Y, Deng X, Landesberg G, Scalia R, Panettieri RA,Mallilankaraman K, Tang XD, Madesh M, Gill DL (2011) Hypoxia-induced acidosis uncouplesthe STIM-Orai calcium signaling complex. J Biol Chem. 286(52):44788-98

        Wang, Y., Deng, X., Hewavitharana, T., Soboloff, J. andGill, D.L. (2008) Stim, ORAI and TRPCchannels in the control of calcium entry signals in smooth muscle. Clin. Exp. Pharmacol. Physiol. 35(9):1127-33

      January 2014

      • 1-15-2014: Publication on line
        Ni, J.*, Zhu, Z., Wang, G., Shen, Y., Zhang, Y. and Wu, P. (2014) Intragenic suppressor of osiaa23 revealed a conserved tryptophan residue crucial for protein-protein interactions. PLoS One, 9, e85358. [Full Text]

      October 2013

      • 10-15-2013: 学术报告 “Biotech Crops: Issues of Science, Perception and the Environment”
        报告人: Dr. James Siedow, 美国DUKE大学科研副校长, Journal of Biological Chemistry副主编
        时间: 2013年10月15日(周二), 14:00-16:00
        地点: 下沙校区图书馆十楼报告厅

      • 10-16-2013: 学术报告 “How to write scientific manuscripts?”
        报告人: Dr. James Siedow
        时间: 2013年10月16日(周三), 14:00-16:00
        地点: 下沙校区叙伦厅

      • 专家简介: James Siedow乃美国DUKE大学科研副校长,杭州师范大学裴真明团队学术顾问,著名植物生物学教授,长期从事有关植物逆境生理及其分子生物学方面的研究,在植物生理学、细胞和生物化学及分子生物学领域都具有很高的造诣。尤其在植物和真菌的代谢过程中的有氧呼吸研究领域作出了突出贡献,克隆了一个高等植物与和许多真菌线粒体中存在的“另类”抗氰氧化酶,并深入研究了其结构和调节功能。同时,他也对拟南芥在不同发育阶段与环境的关系进行过深入的研究,包括极端温度、病原体的感染和营养限制,以及氧化酶活性的调节变化等方面。除此之外,他还兼任多个国际重要期刊的主编和编委。并在高水平SCI期刊上发表论文120余篇,包括Science,Plant Physiology,Plant Cell,PNAS等顶级期刊。
      • 10-04-2013: Publication on line
        Jiang, Z., Zhu, S., Ye R., Xue Y., Chen A., An Li. and Pei Z.M.* (2013) Relationship between NaCl- and H2O2-induced Cytosolic Ca2+ Increases in Response to Stress in Arabidopsis. PLoS One 8(10): e76130. [Full Text]

      August 2013

      • 08-20-2013: 学术报告 “Molecular Characterization of Vacuolar Sorting Receptor-Cargo Interaction in Arabidopsis”
        报告人:Dr. Jinbo Shen (沈锦波),香港中文大学生科院
        时间:2013年8月20日(周二),上午10:00-11:00
        地点:生科院5号实验楼东4楼会议室

      • 08-01-2013: Publication on line
        Zhu, S., Zhou, X., Wu, X. and Jiang, Z.* (2013) Structure and function of the CBL-CIPK Ca2+-decoding system in plant calcium signaling. Plant Mol Biol Rep, 1-10. [Full Text]

      May 2013

      • 05-31-2013: Publication on line
        Wu, X.*, Pang, E., Lin, K. and Pei, Z.M. (2013) Improving the Measurement of Semantic Similarity between Gene Ontology Terms and Gene Products: Insights from an Edge- and IC-Based Hybrid Method. PLoS One 8(5), e66745. [Full Text]

      January 2013

      • 01-15-2013: HRSS software for calculating GO-based semantic similarity is on line. [HRSS webpage]

      • 01-14-2013: CPEsen website is now on line!